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Alpha&ESM hFolds

A database for the comparison of structural models predicted by ESMFold and AlphaFold2 for 42,942 human proteins.
Part of the Bioinformatics Sweeties collection.

Protein information Download JSON
Protein name Galactose-1-phosphate uridylyltransferase
Gene name GALT
UniProt accession P07902
Sequence length 379
Protein source SwissProt (reviewed)
Signal/Transit peptide Absent
Highest-coverage PDB Chain 6gqd_A
PDB Chain coverage 0.91
Experimental method (Resolution) X-ray diffraction (1.52 Å)

Sequence alignment (from structure superimposition) Download FASTA

Model Confidence: Very high (pLDDT ≥ 90) High (90 > pLDDT ≥ 70) Low (70 > pLDDT ≥ 50) Very low (pLDDT < 50)

Structure superimposition
ESMFold
AlphaFold2
Alignment statistics
Structure alignment scores
TM-score 0.9
RMSD 1.99 Å
GDT 0.84
TM-score pLDDT≥50 0.95
TM-score pLDDT≥70 0.98
TM-score pLDDT≥90 0.99
Sequence coverage
ESMFold start - end 20 - 379
AlphaFold2 start - end 21 - 379
Alignment length 362
Match positions 347
Mismatch positions 10
Gap positions (Gap opens) 22 (4)
Model quality statistics
  ESMFold AlphaFold2 Consensus
# of residues with pLDDT ≥ 50 (%) 358 (94.46%) 367 (96.83%) 346 (91.29%)
# of residues with pLDDT ≥ 70 (%) 336 (88.65%) 342 (90.24%) 305 (80.47%)
# of residues with pLDDT ≥ 90 (%) 196 (51.72%) 304 (80.21%) 194 (51.19%)

Sequence alignment (from structure superimposition) Download FASTA

Model Confidence: Very high (pLDDT ≥ 90) High (90 > pLDDT ≥ 70) Low (70 > pLDDT ≥ 50) Very low (pLDDT < 50)

Structure superimposition
ESMFold
PDB (6gqd_A)
Alignment statistics
Structure alignment scores
TM-score 0.92
RMSD 2.3 Å
TM-score pLDDT≥50 0.95
TM-score pLDDT≥70 0.96
TM-score pLDDT≥90 0.98
Sequence coverage
ESMFold start - end 18 - 370
PDB start - end 1 - 344
Alignment length 355
Match positions 318
Mismatch positions 24
ESMFold gap positions 2
PDB gap positions 37
Gap opens 9

Sequence alignment (from structure superimposition) Download FASTA

Model Confidence: Very high (pLDDT ≥ 90) High (90 > pLDDT ≥ 70) Low (70 > pLDDT ≥ 50) Very low (pLDDT < 50)

Structure superimposition
AlphaFold2
PDB (6gqd_A)
Alignment statistics
Structure alignment scores
TM-score 0.97
RMSD 1.28 Å
TM-score pLDDT≥50 0.97
TM-score pLDDT≥70 0.97
TM-score pLDDT≥90 0.99
Sequence coverage
AlphaFold2 start - end 24 - 370
PDB start - end 4 - 344
Alignment length 347
Match positions 330
Mismatch positions 11
AlphaFold2 gap positions 3
PDB gap positions 38
Gap opens 3